DOI: https://doi.org/10.30978/UJDVK2019-2-99

Пробіотики в дерматології

C. Diehl

Анотація


Пробіотики — це живі мікроорганізми, які при введенні в адекватних кількостях можуть принести користь для здоров’я господаря. Ми вже знаємо, що їх використання позитивно впливає на ключові чинники в розвитку дерматологічних захворювань, таких як окиснювальний стрес або запалення. Найбільш популярне використання пробіотиків у дерматології відноситься до атопічного дерматиту (AД). Оскільки вже продемонстровано і широко визнано, що пробіотики можуть допомогти знизити частоту і тяжкість АД у дітей грудного віку, потрібно ще багато дослід­жувати його користь при лікуванні АД у немовлят/дітей, а також і у дорослих. Аналогічним чином багатообіцяючі дані показують, що пробіотики можуть допомогти при вугровій висипці, в загоєнні ран і відновленні тканин. Набагато менше або навіть нічого не відомо про їх потенційний ефект при інших запальних захворюваннях, таких як розацеа або псоріаз. Крім продемонстрованої активності в галузі фотозахисту, пробіотики, мабуть, ефективні для профілактики і навіть лікування старіння шкіри і її більш частих симптомів, таких як втрата колагену, сухість і порушення бар’єрної функції. З огляду на особливий статус шкіри її доступ для місцевого нанесення препаратів, пробіотики можуть використовуватися як системно, так і локально. 
Нормалізація мікрофлори кишечника з використанням пробіотиків і пребіотиків робить позитивний вплив на деякі шкірні захворювання.
Попереду ще довгий і багатообіцяючий шлях для дослідження, перш ніж пробіотики стануть щоденним рецептом в дерматології.
Ми перебуваємо на попередній стадії при використанні пробіотиків у дерматології, і ще потрібно багато досліджень. Одного разу пробіотики стануть частиною дерматологічного рецепта.


Ключові слова


пробіотики; пребіотики; шкіра; запалення; атопічний дерматит; старіння шкіри

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