DOI: https://doi.org/10.30978/UJDVK2018-4-70

Шкірні побічні ефекти онкологічного лікування Частина II. Променева терапія

C. Diehl

Анотація


роменева терапія (ПТ) разом із хіміотерапією є способом лікування хворих зі злоякісними пухлинами. Так само, як і хіміотерапія, ПТ індукує виникнення побічних реакцій з боку шкіри, тяжкість яких значно варіюється, залежно від різних чинників, пов’язаних із лікуванням, таких як загальна доза, наявність чи відсутність фракціонування індивідуальної чутливості пацієнтів. Ці побічні реакції можуть бути гострими, що виникають відразу після проведення ПТ, пролонгованими, які розвиваються через деякий час після припинення процедури, або хронічними, і в цьому випадку можуть тривати багато років і навіть протягом усього життя. Найбільш часті гострі побічні реакції ПТ — гострий променевий дерматит, радіаційні опіки та місцеві запальні реакції в зонах опромінення. Най­поширенішою непрямою реакцією є індукований радіацією фіброз, а серед хронічних побічних ефектів найчастіше спостерігається хронічний променевий дерматит. Окрім профілактичних заходів, ефективність яких обмежена, менеджмент і лікування визнані обов’язковими й мають бути добре відомими дерматологам. Призначення цих процедур залежить від характеру та вираженості побічних реакцій. Цей огляд має на меті поглибити знання про побічні реакції з боку шкіри при ПТ та допомогти хворим, які звертаються по допомогу до фахівця.

Ключові слова


променева терапія; побічні ефекти; радіаційний дерматит; радіаційні опіки; місцеві запальні реакції в зонах опромінення; індукований радіацією фіброз; профілактика; лікування

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Посилання


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